Lowell House was a fraternity house at UC Sunnydale; it was originally known as the Lowell Home for Children, a home for orphan adolescents ran by Genevieve Holt between 1949 and 1960.
The Initiative's secret research lab was built below Lowell House and many agents lived in the house.
The frat boys are Riley Finn, Forrest Gates and Graham Miller. When the children's ghosts, which happened to be the raw emotions in the form of the poltergeist haunt the Lowell house, they shave girls' hair, drown their victims in the bathtub by "baptizing" and possess them by seducing them.